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. 2022 Sep 22;32(11):1377–1386. doi: 10.1136/ijgc-2022-003585

Table 2.

Type of evidence and number of occurrence per selected drug repurposing candidate

Drug In vitro results In vivo results Human results Registered trials in databases
Arsenic trioxide 23 7 0 2
Artesunate 5 4 0 0
Atovaquone 1 1 0 0
Bortezomib 11 4 0 2
Cetuximab 7 2 8 8
Chlorpromazine 3 0 1 0
Cidofovir 6 6 3 2
Decitabine 21 0 2 0
Deferoxamine 2 2 0 0
Doxycycline 4 3 0 1
Erlotinib 4 1 4 2
Everolimus 3 0 1 2
Fulvestrant 3 1 0 1
Gefitinib 4 0 4 2
Hydralazine 7 1 3 3
Interferon α-2b 9 2 18 1
Ipilimumab 0 0 2 6
Lovastatin 3 0 1 0
Lurbinectedin 2 2 0 0
Melatonin 5 2 0 0
Metformin 20 6 4 3
Mifepristone 9 2 0 0
Nelfinavir 6 3 0 3
Niclosamide 1 0 0 0
Nicotinamide 1 1 1 0
Niraparib 0 0 0 4
Olaparib 4 2 0 6
Pazopanib 0 0 1 3
Plerixafor 4 3 0 0
Porfimer 2 0 1 0
Ribavirin 2 2 0 0
Ribociclib 2 1 0 0
Rucaparib 2 1 0 3
Ruxolitinib 1 1 0 0
Sacituzumab govitecan 1 1 0 0
Sonidegib 1 1 0 0
Valproic acid 11 7 3 4
Zoledronic acid 4 2 0 1