Table 2.
Proposed common ground for dietary therapy in CD and UC
Rationale | Recommendation | |
Disallow | ||
Artificial sweetener (sacchrine, splenda) | Experimentally promoting gut inflammation,92 94 altering human gut microbiota,93 restriction in nutritional trials39–41 | Stop ultra-processed, ready-made or canned food, sweets, soft drinks |
Emulsifiers (P80, CMC) | Experimentally promoting gut inflammation,31 altering human gut microbiota,96 restriction in nutritional trials39–41 | Stop ultra-processed, ready-made or canned food, sweets, soft drinks |
Food colourants (Red 40/E129, Yellow 6/E110) | Experimentally promoting gut inflammation,30 restriction in nutritional trials39–41 | Stop ultra-processed, ready-made or canned food, sweets, soft drinks |
Ultra-processed food | Experimentally promoting gut inflammation (see additives above), restriction in nutritional trials39–41 | Stop ultra-processed, ready-made or canned food, sweets, soft drinks |
Restrict | ||
Saturated and polyunsaturated fatty acids | Experimentally promoting gut inflammation,36 38 arguably restriction in nutritional trials39–41 | Restrict animal fat (regardless of source), deep fried and ultra-processed food |
Sucrose, Glucose, Fructose | Experimentally promoting gut inflammation,23–27 arguably restriction in nutritional trials39–41 | Restrict soft drinks, sweets, ready- made food |
Enrich | ||
Plant-based food items (fibre source) | Enrichment in nutritional trials39–41 | Encourage plant-based diet |
Dietary counselling recommendation based on experimental evidence and nutritional trials. Note that the efficacy and safety of the proposed dietary alterations requires corroboration by controlled nutritional trials in patients with IBD.
CD, Crohn’s disease; IBD, inflammatory bowel disease; UC, ulcerative colitis.