Table 1.
Summary of clinical and demographic data for patients whose tumor material was used to generate the JAX collection of lung cancer PDX models.
| Characteristics | Adenocarcinoma (LUAD) | Squamous cell carcinoma (LUSC) | All other lung cancers |
|---|---|---|---|
| N = | 37 | 33 | 9 |
| Age | |||
| Median (range) | 58 (42–79) | 67 (50–85) | 60 (50–780 |
| Sex | |||
| Female/male | 24/13 | 12/21 | 8/1 |
| Race/ethnicity | |||
| White/Not Hispanic | 22 | 16 | 6 |
| White/Not reported | 5 | 11 | 1 |
| White/Hispanic | 1 | 0 | 0 |
| Asian or Pacific Islander/Not Hispanic | 5 | 1 | 0 |
| American Indian or Alaskan Native/Not Hispanic | 1 | 1 | 0 |
| American Indian or Alaskan Native/Hispanic | 0 | 1 | 0 |
| Not Reported/Not Hispanic | 1 | 1 | 0 |
| Not Reported/Not reported | 2 | 2 | 2 |
| Tumor type | |||
| Primary/relapse/metastatic | 22/1/14 | 31/1/1 | 7/0/2 |
| Stage | |||
| I (A,B) | 4 | 7 | 2 |
| II (A,B) | 5 | 9 | 0 |
| III (A,B) | 5 | 9 | 3 |
| IV (A,B) | 23 | 4 | 3 |
| Not reported | 0 | 4 | 1 |
| Smoking status | |||
| Smoker | 7 | 6 | 3 |
| Former | 15 | 17 | 3 |
| Never | 6 | 0 | 0 |
| Unknown | 9 | 10 | 3 |
| Treatment naïve? | |||
| Y/N/unknown | 19/16/2 | 30/2/1 | 5/3/1 |