Table 3.

Correlation analysis between monocyte and variables at the time of biologic discontinuation using Pearson correlation analysis.

Crohn’s disease (N = 159)		Variables at biologic discontinuation
Monocyte		Duration of biologics treatment	Hematocrit	Albumin	ESR	CRP	Calprotectin	PCDAI	SES-CD	Time to relapse after D/C
Percentage of WBC	Pearson coefficient	-0.022	-0.145	-0.326**	0.299**	0.314**	0.371**	0.088	0.318**	-0.283**
	P-value	0.781	0.069	<0.001	<0.001	<0.001	0.005	0.272	<0.001	0.001
Absolute count	Pearson coefficient	0.003	-0.119	-0.344**	0.339**	0.379**	0.385**	0.168*	0.422**	-0.107
	P-value	0.973	0.134	<0.001	<0.001	<0.001	0.003	0.034	<0.001	0.236
Monocyte/PMN ratio	Pearson coefficient	-0.125	-0.230**	-0.346**	0.292**	0.288**	0.353**	0.197*	0.242**	-0.031
	P-value	0.115	0.004	<0.001	<0.001	<0.001	0.007	0.013	0.002	0.729
Ulcerative colitis (N = 29)		Variables at biologic discontinuation
Monocyte		Duration of biologics treatment	Hematocrit	Albumin	ESR	CRP	Calprotectin	PUCAI	MES	Time to relapse after D/C
Percentage of WBC	Pearson coefficient	0.344	0.024	0.007	0.193	0.256	-0.070	-0.064	-0.201	-0.300
	P-value	0.067	0.903	0.970	0.317	0.180	0.762	0.743	0.295	0.114
Absolute count	Pearson coefficient	-0.076	0.092	-0.202	0.629**	0.721**	0.210	0.584**	0.392*	0.219
	P-value	0.694	0.634	0.293	<0.001	<0.001	0.361	0.001	0.035	0.254
Monocyte/PMN ratio	Pearson coefficient	0.316	0.353	-0.111	0.329	0.648**	0.050	0.259	0.148	-0.066
	P-value	0.095	0.060	0.565	0.082	<0.001	0.829	0.175	0.444	0.734

*P < 0.05, **P < 0.01 level (two-tailed).

Bold values mean statistically significant values with p-value <0.05.