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. 2022 Nov 9;15(11):e250852. doi: 10.1136/bcr-2022-250852

Table 1.

Previously reported cases of hyperammonaemia syndrome secondary to Ureaplasma spp infection outside the lung transplant population

Case/(reference) Year published Age Sex Risk factor Site of infection Species Diagnostic test Treatment Outcome
1/10 2020 16 F Newly diagnosed acute myeloid leukaemia undergoing induction chemotherapy Primary site not identified U. parvum PCR on blood Doxycycline Alive
2/11 2019 32 F Acute lymphoblastic leukaemia undergoing salvage chemotherapy Primary site not identified U. urealyticum PCR on blood Levofloxacin Died
3/12 2018 21 M Post stem cell transplant for acute myeloid leukaemia Pneumonia U. parvum PCR on tracheal aspirate Azithromycin+levofloxacin Alive
4/13 2021 53 F Chimeric receptor antigen T-cell recipient for relapsed acute lymphoblastic leukaemia Pneumonia Not specified PCR on BAL fluid Levofloxacin Died
5/14 2020 16 F Kidney transplant Joint (polyarthritis) U. urealyticum PCR on blood, urine, synovial fluid Doxycycline+levofloxacin Alive
6/15 2020 53 F Liver-kidney transplant Endovascular infection+Peritonitis Not specified PCR on intra-abdominal collections and stent Doxycycline+levofloxacin Alive
7/16 2020 56 F Kidney transplant Urinary tract Not specified 16s on urine Moxifloxacin+doxycycline Alive
8/17 2020 65 F Kidney transplant Surgical site infection “chronic scar infection post kidney transplant” U. parvum PCR on blood and urine Doxycycline+levofloxacin Died

BAL, Bronchoalveolar lavage; F, female; M, male.