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. 2022 Sep 20;6(11):e10672. doi: 10.1002/jbm4.10672

Table 1.

Selected Participant Characteristics by Treatment

Variables All patients (n = 71) Conventional treatment (n = 38) Burosumab treatment (n = 33) Comparison between conventional treatment and burosumab (p)
Sex, n (%)
Male 30 (42.3) 16 (42.1) 14 (42.4)
Female 41 (57.7) 22 (57.9) 19 (57.6) 0.98
Age at XLH treatment onset (years), mean ± SD 5.45 ± 4.34 2.92 ± 3.0 8.36 ± 3.81 0.00001
XLH treatment duration (months), mean ± SD 70.5 ± 49.2 97.9 ± 46.9 38.9 ± 29.0 0.0001
Alkaline phosphatase level (IU/L), mean ± SD 364.4 ± 138.9 385.8 ± 147.7 339.8 ± 125.7 0.17
Age at dental follow‐up onset (years), mean ± SD 7.86 ± 3.76 6.58 ± 3.33 9.33 ± 3.72 0.004
Dental follow‐up duration (months), mean ± SD 41.5 ± 27.5 53.9 ± 31.9 27.2 ± 9.6 0.0009
Number of dental abscess per month of dental follow‐up (n/month), mean ± SD 0.03 ± 0.04 0.04 ± 0.05 0.01 ± 0.03 0.04
Number of maxillofacial cellulitis per month of dental follow‐up (n/month), mean ± SD 0.004 ± 0.02 0.007 ± 0.02 0.002 ± 0.008 0.23
Dental caries during dental follow‐up, n (%) 13 (18.3) 7 (18.4) 6 (18.2) 0.98