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. 2022 Sep 20;6(11):e10672. doi: 10.1002/jbm4.10672

Table 3.

Comparison of Selected Participant Characteristics in Patients Who Had Conventional Treatment and then Burosumab Treatment

Variables Conventional treatment (n = 19) Burosumab treatment (n = 19) p
Sex, n (%)
Male 7 (36.9) 7 (36.9)
Female 12 (63.1) 12 (63.1) 1
Age at XLH treatment onset (years), mean ± SD 2.10 ± 2.07 9.75 ± 2.92 <0.0001
XLH treatment duration (months), mean ± SD 90.8 ± 36.3 35.0 ± 7.1 <0.0001
Alkaline phosphatase level (IU/L), mean ± SD 451.0 ± 147.2 297.8 ± 100.2 <0.0001
Age at dental follow‐up onset (years), mean ± SD 6.60 ± 3.67 10.36 ± 3.11 <0.0001
Dental follow‐up duration (months), mean ± SD 37.2 ± 27.8 27.7 ± 8.1 0.19
Number of dental abscess per month of dental follow‐up (n/month), mean ± SD 0.08 ± 0.1 0.007 ± 0.02 0.01
Number of maxillofacial cellulitis per month of dental follow‐up (n/month), mean ± SD 0.005 ± 0.02 0.002 ± 0.009 0.43
Dental caries during dental follow‐up, n (%) 2 (10.5) 4 (21.0) 0.68