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QCT measured changes (mean ± SD) at 14 months in TBD in distal tibia. TBD did not change in placebo (circles, 0.2% below baseline, p = 0.43), in some contrast with TBD increases typical to healthy boys of the same age.( 73 ) LIV increased TBD by 4.6% (squares, p < 0.20 from baseline). Unfortunately, because of the loss of subject‐specific compliance records, the ability to correlate non‐responders (eg, two LIV subjects that lost TBD) to their daily use of the device was not possible.
