Table 3.
Factors associated with infection in univariate analysis using Cox regression
| Factors | HR (95% CI) | P-value |
|---|---|---|
| Age (per 10 years) | 1.18 (1.05–1.33) | .005 |
| Sex (male) | 1.04 (0.75–1.44) | .818 |
| Diabetes (yes) | 1.32 (0.94–1.85) | .107 |
| Hypertension (yes) | 1.03 (0.74–1.43) | .875 |
| Dyslipidaemia (yes) | 0.89 (0.64–1.24) | .499 |
| Coronary artery disease (yes) | 0.82 (0.50–1.36) | .452 |
| Heart failure (yes) | 0.84 (0.54–1.30) | .428 |
| Peripheral vascular disease (yes) | 1.43 (0.73–2.83) | .298 |
| Atrial fibrillation (yes) | 0.98 (0.66–1.45) | .913 |
| Stroke (yes) | 1.08 (0.68–1.73) | .742 |
| Malignancy (yes) | 1.08 (0.75–1.56) | .683 |
| Cognitive impairment (yes) | 1.51 (1.00–2.28) | .050 |
| Baseline RAASi | 1.07 (0.78–1.47) | .657 |
| Baseline diuretics | 1.03 (0.74–1.44) | .863 |
| Baseline eGFR (per 10 ml/min/1.73 m2) | 0.91 (0.83–1.01) | .069 |
| Nadir eGFR (per 10 ml/min/1.73 m2) | 0.97 (0.90–1.05) | .419 |
| Immediate eGFR after AKI (per 10 ml/min/1.73 m2) | 0.96 (0.91–1.02) | .196 |
| eGFR 3 months after AKI (per 10 ml/min/1.73 m2) | 0.91 (0.86–0.97) | .002 |
| eGFR loss from baselinea (per 10 ml/min/1.73 m2) | 1.07 (1.01–1.14) | .028 |
| AKI-to-CKD transition (yes) | 1.55 (1.13–2.14) | .007 |
| Albumin:creatinine ratio (mg/g) | 1.00 (0.99–1.00) | .757 |
| Serum albumin (g/dl) | 1.05 (0.99–1.13) | .100 |
RAASi: renin–angiotensin–aldosterone system inhibitor.
Statistically significant values in bold.
a
eGFR loss from baseline to 3 months after the peak serum creatinine was reached in the AKI episode.