Table 4.
Independent predictors for infection using Cox regression in adjusted models
| Crude | Model 1 | Model 2 | Model 3 | |||||
|---|---|---|---|---|---|---|---|---|
| Predictors | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value |
| AKI-to-CKD transition (yes) | 1.55 (1.13–2.14) | .007 | 1.40 (1.01–1.94) | .044 | 1.39 (1.00–1.94) | .049 | 1.47 (1.01–2.15) | .043 |
| 3-month eGFRa (per 10 ml/min/1.73 m2) | 0.91 (0.86–0.97) | .002 | 0.93 (0.87–0.99) | .035 | 0.93 (0.88–0.99) | .048 | 0.91 (0.85–0.98) | .015 |
| eGFR lossb (per 10 ml/min/1.73 m2) | 1.07 (1.01–1.14) | .028 | 1.06 (1.01–1.13) | .046 | 1.06 (0.99–1.13) | .091 | 1.09 (1.02–1.17) | .015 |
Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex and cognitive impairment. Model 3 was adjusted for baseline, nadir and post-AKI eGFR.
a
eGFR assessment 3 months after the peak serum creatinine was reached in the AKI episode (AKI-to-CKD assessment).
b
eGFR loss from baseline to 3 months after discharge from the AKI episode (AKI-to-CKD assessment).