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. 2022 Aug 3;15(12):2228–2236. doi: 10.1093/ckj/sfac176

Table 4.

Factors associated with CKD in the Meinian Onehealth study

CKD Creatinine eGFR
Factors OR (95% CI) P-value β (SE) P-value β (SE) P-value
Age, per 10-year increment 3.05 (3.02–3.09) <.001 0.712 (0.006) <.001 −7.350 (0.006) <.001
Female 1.81 (1.77–1.85) <.001 −17.09 (0.018) <.001 1.064 (0.018) <.001
North residence 0.56 (0.55–0.58) <.001 −3.616 (0.015) <.001 4.073 (0.015) <.001
BMI (kg/m2) 0.93 (0.91–0.93) <.001 −0.363 (0.008) <.001 0.217 (0.008) <.001
Stroke (yes/no) 1.37 (1.26–1.48) <.001 1.473 (0.138) −0.466 (0.022) <.001
Coronary heart disease (yes/no) 1.32 (1.27–1.40) <.001 1.581 (0.077) <.001 −1.523 (0.076) <.001
Diabetes (yes/no) 1.35 (1.31–1.39) <.001 −2.262 (0.033) <.001 1.857 (0.032) <.001
Hypertension (yes/no) 1.51 (1.47–1.56) <.001 0.577 (0.023) <.001 −0.466 (0.022) <.001
Systolic BP (mmHg) 1.03 (1.02–1.05) <.001 −0.198 (0.010) <.001 0.212 (0.010) <.001
Diastolic BP (mmHg) 0.90 (0.89–0.91) <.001 −0.283 (0.009) <.001 0.153 (0.009) <.001
HR (bpm) 1.05 (1.04–1.06) <.001 −0.112 (0.006) <.001 0.262 (0.006) <.001
HDL (mmol/l) 1.11 (1.10–1.12) <.001 0.448 (0.008) <.001 −0.613 (0.007) <.001
LDL (mmol/l) 0.94 (0.92–0.95) <.001 −0.011 (0.010) .261 0.104 (0.010) <.001
TC (mmol/l) 1.00 (0.98–1.01) .880 0.407 (0.011) <.001 −0.566 (0.011) <.001
TG (mmol/l) 1.08 (1.07–1.10) <.001 0.041 (0.008) <.001 −0.251 (0.008) <.001
Fasting glucose (mg/dl) 0.97 (0.96–0.98) <.001 −0.046 (0.007) <.001 −0.020 (0.007) .005
UA (µmol/l) 2.18 (2.15–2.20) <.001 3.201 (0.008) <.001 −2.882 (0.008) <.001

Data are presented as multivariable-adjusted OR (95% CI).

ORs were calculated with the use of multinomial logit models.

All covariables listed were included in the model simultaneously.

Hypertension was defined as systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg or a self-reported history of hypertension.

Diabetes was defined as fasting glucose ≥7.0 mmol/l or haemoglobin A1c ≥6.5% or a self-reported history of diabetes.

SE: standard error.