TABLE 4.
H. ducreyi hemolysin is cytotoxic to mononuclear cells but not PMNs
| Strain | Normalized LDH releasea from:
|
|
|---|---|---|
| Mononuclear cells | PMNs | |
| 35000 | 0.00 ± 0.02 | 0.26 ± 0.22 |
| 35000ΔAPC | 0.12 ± 0.03 | 0.41 ± 0.06 |
| 35000ΔAPC(pLSSK) | 0.00 ± 0.11 | 0.32 ± 0.25 |
| 35000ΔAPC(pLSBA+2) | 1.52 ± 0.11 | 0.18 ± 0.20 |
| 35000ΔAPC(pLS384-2) | 44.53 ± 4.46 | 0.85 ± 0.14 |
| 35000ΔAPC(pLSB+) | 0.00 ± 0.25 | 0.15 ± 0.22 |
a
Values represent normalized LDH release and are the average of quadruplicate samples ± standard error. The results of a typical experiment are shown; the experiment was repeated twice with mononuclear cells and three times with PMNs with similar results.