FIG 3.
Probability of target attainment (PTA) for meropenem regimens achieving 75% fT>MIC target during 24 to 48 h after administration. Five groups were categorized according to creatinine clearance calculated by the Cockcroft and Gault equation (CLCR-CG) as <10 mL/min (A), 10 to 25 mL/min (B), >25 to 50 mL/min (C), >50 to 90 mL/min (D), and >90 to 130 mL/min (E). (F) A histogram showing international MIC distribution of meropenem for Pseudomonas aeruginosa and Acinetobacter baumannii from the EUCAST database (October 2021) is shown. The horizontal dashed line denotes the PTA of 90%; LD, loading dose.