TABLE 4.
Comparison of baseline characteristics between clinical success and failure groups
| Clinical outcomeb |
Survival during ICU admissionb |
|||
|---|---|---|---|---|
| Characteristica | Success (n = 13) | Failure (n = 7) | Alive (n = 14) | Dead (n = 6) |
| Male | 7 (53.8) | 3 (42.9) | 7 (50) | 3 (50) |
| Age (yrs) | 63.3 (55.2 to 76.5) | 65.1 (63 to 71.6) | 61.8 (46.4 to 75.7) | 67.3 (64.0 to 72.8) |
| Body wt (kg) | 62 (51 to 68) | 60 (59 to 67.2) | 59.5 (50.8 to 67.6) | 62.5 (60 to 68.2) |
| APACHE IIc | 20 (19 to 22) | 28 (16.5 to 29.5) | 20 (17.5 to 21.8) | 28 (20.5 to 30.3) |
| SOFAc | 9 (6 to 11) | 10 (8 to 12) | 8 (6.0 to 10.8) | 10 (8.5 to 13.0) |
| Inotropic or vasopressor used | 10 (76.9) | 7 (100) | 11 (78.6) | 6 (100) |
| Mechanical ventilator | 11 (84.6) | 7 (100) | 12 (85.7) | 6 (100) |
| Sepsisd | 13 (100) | 7 (100) | 14 (100) | 6 (100) |
| Septic shockd | 6 (46.2) | 4 (57.1) | 6 (42.9) | 4 (66.7) |
| CLCR-CG (mL/min) | 45.5 (38.6 to 84.5) | 69.2 (30.5 to 82.1) | 46.7 (39 to 84.3) | 52.9 (27.4 to 77.6) |
| Serum lactate (mmol/L) | 2.3 (1.6 to 6.1) | 4 (1.8 to 7.1) | 2.3 (1.3 to 5.6) | 4.1 (2.5 to 8.5) |
| Hypoalbuminemia | 9 (69.2) | 6 (85.7) | 10 (71.4) | 5 (83.3) |
| Primary infection site | ||||
| Respiratory | 6 (46.1) | 7 (100) | 8 (57.1) | 5 (83.3) |
| Genitourinary | 3 (23.1) | 0 | 3 (21.4) | 0 |
| Intraabdominal | 2 (15.4) | 0 | 1 (7.1) | 1 (16.7) |
| Others | 2 (15.4) | 0 | 2 (14.3) | 0 |
| MIC (mg/L) | 0.032 (0.023 to 32)e | 32 (12 to 32)e | 0.07 (0.023 to 32)e | 32 (12 to 32)e |
| Meropenem monotherapy | 12 (92.3) | 2 (28.6) | 13 (92.9) | 1 (16.7) |
| Concomitant antimicrobials | ||||
| Colistin | 1 (7.7) | 3 (42.8) | 1 (7.1) | 4 (66.7) |
| Vancomycin | 0 | 1 (14.3) | 0 | 1 (16.7) |
| Other | 0 | 1 (14.3) | 0 | 0 |
a
The information was from the first day of infection.
b
Data are expressed as n (%) or median (interquartile range), unless otherwise stated.
c
Evaluation on the first day of ICU admission.
d
Patient diagnosed according to sepsis-3 criteria.
e
Median (minimum-maximum).