TABLE 1.
Core regulon of Rgg2/3 QSa
| Locus tag | Predicted or known functionb | Predicted protein localizationc | Log2FCd NZ131 + SHP vs NZ131 | Log2FC Δrgg3 vs Δrgg2 | Log2FC Δrgg3 + SHP vs Δrgg2 + SHP |
|---|---|---|---|---|---|
| spy49_0414c | StcA, lysozyme resistance and biofilm formation | Extracellular | 9.31 | 10.44 | 11.15 |
| spy49_0450 | AroE.2, shikimate dehydrogenase | Unknown | 8.71 | 10.72 | 9.16 |
| spy49_0451 | Sugar isomerase | Cytoplasmic | 8.79 | 10.34 | 9.04 |
| spy49_0453 | F420-dependent γ-glutamyl ligase | Cytoplasmic | 8.45 | 10.02 | 9.07 |
| spy49_0454 | Oxidoreductase | Cytoplasmic | 8.67 | 9.81 | 9.26 |
| spy49_0455 | Archaeal metK SAM synthetase | Cytoplasmic | 8.36 | 9.34 | 8.87 |
| spy49_0456 | Hpr kinase/phosphatase domain | Unknown | 8.36 | 9.28 | 8.80 |
| spy49_0457 | Glycosyltransferase | Cytoplasmic membrane | 8.34 | 9.07 | 8.87 |
| spy49_0458 | Pseudogene; acyl carrier protein or nonribosomal peptide synthetase | Unknown | 8.01 | 8.70 | 8.92 |
| spy49_0459 | Nucleotide sugar dehydrogenase | Cytoplasmic | 8.00 | 8.54 | 8.68 |
| spy49_0460 | Putative efflux protein | Cytoplasmic membrane | 8.14 | 8.48 | 8.67 |
a
Genes that were observed to be differentially regulated. All genes had a greater than 2-fold log2 fold change, and a q-value of less than 0.05.
b
Predicted function as experimentally validated for StcA in Gogos et al. (5) as determined by protein homology in Rahbari et al. (9) or via BLASTp of protein coding sequences. For further details see Materials and Methods.
c
Cell localization as predicted by PSORTb, only StcA has been experimentally validated as having extracellular localization in Gogos et al. (5). For further details see Materials and Methods.
d
Log2FC indicates log2 fold change.