Table 1.
Number of Samples Tested and Results From Each Collection Technique, by M. tuberculosis Detection Method
| Fluorescence Microscopy, No. (%) | Xpert Only, No. (%) | MGIT Only, No. (%) | Xpert or MGIT, No. (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Mtb Negative | Mtb Positive | Total | Mtb Negative | Mtb Positive | Total | Mtb Negative | Mtb Positive | Total | Mtb Negative | Mtb Positive | ||
| Samples from invasive techniques | |||||||||||||
| Gastric aspirate | 561 | 553 (99) | 8 (1) | 562 | 538 (96) | 24 (4) | 530 | 495 (93) | 35 (7) | 562 | 523 (93) | 39 (7) | |
| Induced sputum | 544 | 538 (99) | 6 (1) | 543 | 524 (97) | 19 (3) | 517 | 489 (95) | 28 (5) | 543 | 511 (94) | 32 (6) | |
| Samples from non- or minimally invasive techniques | |||||||||||||
| Nasopharyngeal aspirate | 566 | 556 (98) | 10 (2) | 566 | 543 (96) | 23 (4) | 524 | 489 (93) | 35 (7) | 566 | 527 (93) | 39 (7) | |
| Stool | 507 | 501 (99) | 6 (1) | 506 | 487 (96) | 19 (4) | 438 | 427 (97) | 11 (3) | 510 | 487 (95) | 23 (5) | |
| String test | 542 | 539 (99) | 3 (1) | 540 | 526 (97) | 14 (3) | 524 | 504 (96) | 20 (4) | 542 | 519 (96) | 23 (4) | |
| Blooda | 0 | … | … | 0 | … | … | 96 | 95 (99) | 1 (1) | 96 | 95 (99) | 1 (1) | |
| FNAb | 2 | 2 (100) | 0 (0) | 14 | 11 (79) | 3 (21) | 13 | 10 (77) | 3 (23) | 14 | 10 (71) | 4 (29) | |
| Urinea | 377 | 376 (100) | 1 (0) | 374 | 368 (98) | 6 (2) | 327 | 324 (99) | 3 (1) | 377 | 371 (98) | 6 (2) | |
Abbreviations: FNA, cervical lymph node fine needle aspiration; MGIT, liquid culture for Mycobacteria Growth Indicator Tube; Mtb, Mycobacterium tuberculosis; Xpert, rapid cartridge-based nucleic acid amplification test (Xpert MTB/RIF).
a
Collection and testing of urine and blood specimens were changed based on interim review of assay yields; blood was discontinued after 135 children, and urine was reduced to 1 sample per child after the first 138 children.
b
FNA only collected when indicated (cervical lymphadenopathy).