Table 4.
Prevalence of metabolic disorders in subjects with familial partial lipodystrophy, FPLD3 and FPLD2
| FPLD3 | FPLD2 | |||||
|---|---|---|---|---|---|---|
| N Affected/Total | % Affected | N Affected/Total | % Affected | P value | P value Adjusted for sex and age | |
| Diabetes mellitus | 23/32 | 72.0 | 103/235 | 44.0 | .003 | .02 |
| Hypertriglyceridemia | 26/31 | 84.0 | 140/212 | 66.0 | .05 | .10 |
| Acute Pancreatitis | 15/29 | 52.0 | 32/238 | 13.0 | <.0001 | <.0001 |
| Fatty Liver | 15/28 | 54.0 | 23/51 | 45.0 | .47 | .32 |
| Hypertension | 12/30 | 40.0 | 99/239 | 41.0 | .88 | .41 |
| Proteinuria | 7/27 | 26.0 | 25/200 | 13.0 | .06 | .12 |
| CHD | 5/27 | 19.0 | 36/237 | 15.0 | .65 | .91 |
| PCOS | 14/27 | 52.0 | 42/161 | 26 | .007 | .009 |
Abbreviations: CHD, coronary heart disease; PCOS, polycystic ovarian syndrome.