Table 1.
Characteristics at enrollment of subjects in the two groups followed for 1 year, mean ± SD or n (%)
| Variables | Combination group (n = 27) | Control group (n = 26) |
|---|---|---|
| Age (year) | ||
| All | 10.07 ± 1.44 | 9.80 ± 1.64 |
| Age (8.0 to10.0 years) | 9.77 ± 1.26 (n = 13) | 9.65 ± 1.45 (n = 12) |
| Age (10.1 to 12.0 years) | 10.34 ± 1.58 (n = 14) | 9.98 ± 1.89 (n = 14) |
| Spherical equivalent refraction (SER, D) | ||
| All | -2.81 ± 0.92 | -2.81 ± 0.97 |
| SER (-1.00 to -2.50D) | -2.61 ± 1.04 (n = 14) | -2.76 ± 1.24 (n = 13) |
| SER (-2.51 to -4.00 D) | -3.10 ± 0.68 (n = 13) | -2.84 ± 0.71 (n = 13) |
| Body mass index (kg/m2) | 18.94 ± 4.12 | 17.48 ± 3.40 |
| Age at myopia diagnosis (year) | 8.80 ± 1.50 | 8.84 ± 1.66 |
| Age at first wearing of glasses (year) | 9.06 ± 1.62 | 8.83 ± 1.59 |
|
SER progression 1 year before study enrollment (D) |
-0.72 ± 0.48 | -0.77 ± 0.38 |
| Corneal curvature (D) | 42.84 ± 1.38 | 42.88 ± 1.25 |
| Corneal astigmatism (D) | 1.07 ± 0.48 | 1.23 ± 0.44 |
| Anterior chamber depth (mm) | 3.59 ± 0.42 | 3.70 ± 0.25 |
| Intraocular pressure (mmHg) | 16.96 ± 3.13 | 16.47 ± 2.43 |
| Pupil diameter (mm) | 5.58 ± 1.48 | 5.72 ± 1.19 |
| Accommodative amplitude (D) | 16.11 ± 3.67 | 15.99 ± 4.03 |
| Axial length (mm) | 24.79 ± 0.72 | 24.64 ± 0.79 |
| Male, n (%) | 10 (37.04%) | 15 (57.69%) |
| Heredity | ||
| - - (neither parent myopic) | 2 (7.41%) | 5 (20.00%) |
| + - (one parent myopic) | 11 (40.74%) | 9 (36.00%) |
| + + (both parents myopic) | 14 (51.85%) | 11 (44.00%) |
Note: Combination group: combination of OK lens and 0.01% atropine eye drops; Control group: combination of OK lens and placebo