Table 2.

Measurements of axial length, pupil diameter and accommodative amplitude over time in two groups

	Combination group (n = 27)	Control group (n = 26)	P value
			Group	Time	Group * Time
Axial length (mm)			0.27	<0.001	0.02
Baseline	24.84 ± 0.76	24.70 ± 0.74
4 months	24.83 ± 0.70	24.75 ± 0.71
8 months	24.87 ± 0.75	24.81 ± 0.69
12 months	24.94 ± 0.79	24.90 ± 0.80
Accommodative amplitude (D)			0.65	0.08	0.64
Baseline	16.70 ± 3.47	16.67 ± 3.99
4 months	15.00 ± 2.61	15.47 ± 2.42
8 months	15.22 ± 2.73	15.52 ± 2.63
12 months	15.12 ± 3.19	15.38 ± 2.92
Pupil diameter(mm)			0.61	0.06	0.04
Baseline	5.72 ± 1.42	5.87 ± 1.39
4 months	6.19 ± 1.30	5.71 ± 1.32
8 months	6.14 ± 1.26	5.78 ± 1.40
12 months	6.11 ± 1.45	5.84 ± 1.60

Note: Two-factor repeated measures ANOVA were performed for the axial length, accommodative amplitude, and pupil diameter at each time point with treatment group (combination and control groups), time, and interaction of time and group