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. 2022 Nov 14;60(1):2145–2154. doi: 10.1080/13880209.2022.2136207

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Bioinformatics screening of veratramine target proteins. (A) Veratramine was visualised by docking with SHH protein, and its docking binding energy was –12.8 kcal/mol; (B) Veratramine was visualised by docking with SIGMAR1 protein, and its docking binding energy was –13.6 kcal/mol; (C) qPCR was used to detect SHH gene expression levels in the spinal cord tissues of rats in each group; (D) The spinal cord tissues of rats in each group were examined for SIGMAR1 gene expression levels by qPCR. **p < 0.01, vs. vehicle group, ^##p < 0.01, vs. model group.