FIG. 5.

The average lysis level of 21-4L targets by anti-Y. pseudotuberculosis CTL is lower than that of nontransgenic LEW targets. LN cells from nontransgenic LEW or 21-4L rats infected with Y. pseudotuberculosis(pYV⁺) were restimulated in vitro with Y. pseudotuberculosis(pYV⁺)-infected syngeneic LN cells and tested in parallel for lysis of infected nontransgenic LEW (open bars) or 21-4L (closed bars) or uninfected (hatched bars) lymphoblast targets at effector/target cell ratio of 100. Results are expressed as mean specific percent of lysis + standard error of the mean of targets in 7 (nontransgenic LEW CTLs) and 13 (21-4L CTLs) separate experiments. ∗, P < 0.04, nontransgenic LEW versus 21-4L targets, for nontransgenic LEW CTLs.