FIGURE 1.

Cell size differences among different cell types and species. (A) In the human body, cells of different cell types can vary significantly in their size. Cell images are shown at the same magnification, adapted with permission from HistologyGuide.org. (B) Cell size differences in murine pancreatic cells. Note the pancreatic beta cells in the islet (insulin positive) have much smaller size than the surrounding acinar cells (insulin negative). Adapted from (Anzi et al., 2018). (C) Cell size in the retina not only differs by cell type (cone vs. rod) but also by the location in the tissue (fovea vs. periphery). Note that the cone cells are smaller in the fovea than ones in the periphery, which directly corresponds with the retina’s local visual resolution. Image is from (Curcio et al., 1990). (D) Pancreatic acinar cells vary in size in different mammalian species, from left to right are the Etruscan shrew, mouse, fruit bat, mountain gazelle, and human (tissue section images from Yuval Dor’s lab and animal images searched from Google).