Table 9.
The comparison of laboratory findings between PE and non-PE patients with COVID-19.
| Laboratory indicators | Sample size | Pooled results | Analytic effect model | ||
|---|---|---|---|---|---|
| Estimate | 95% CI | P value | |||
| Serum D-dimer, μg/mL | |||||
| Baseline | 2703 | MD 5.98 | 4.15, 7.81 | < 0.0001 | Random-effect model |
| Peak | 30 | MD 1.10 | 0.13, 2.07 | 0.03 | Fixed effect model |
| Prior to CTPA | 30 | MD 1.00 | –0.17, 2.17 | 0.09 | Fixed effect model |
| Ferritin, ng/mL | |||||
| Baseline | 165 | MD -213.68 | –916.29, 488.93 | 0.98 | Random-effect model |
| Peak | 30 | MD -20.82 | –1373.57, 1331.94 | 0.07 | Fixed effect model |
| Prior to CTPA | 30 | MD -1150.0 | –2390.38, 90.38 | 0.71 | Fixed effect model |
| Platelets, 103/μL | |||||
| Baseline | 1616 | MD 0.49 | –39.76, 40.75 | 0.98 | Random-effect model |
| Peak | 30 | MD -55.0 | –147.31, 37.31 | 0.24 | Fixed effect model |
| Prior to CTPA | 30 | MD 12.0 | –24.84, 48.84 | 0.52 | Fixed effect model |
| Lymphocytes | |||||
| Baseline | 1641 | SMD -0.12 | -0.37, 0.14 | 0.37 | Random-effect model |
| Peak | 30 | SMD -0.34 | –1.06, 0.38 | 0.35 | Fixed effect model |
| Prior to CTPA | 30 | SMD -0.68 | –1.42, 0.06 | 0.07 | Fixed effect model |
| NLR | |||||
| Baseline | 165 | MD 2.17 | –0.54, 4.89 | 0.12 | Fixed effect model |
| Peak | 30 | MD 3.70 | –5.15, 12.55 | 0.41 | Fixed effect model |
| Prior to CTPA | 30 | MD 2.20 | –0.25, 4.65 | 0.08 | Fixed effect model |
| IL-6, pg/mL | 207 | MD -2.23 | –33.02, 28.56 | 0.89 | Fixed effect model |
| NT-pro BNP, pg/mL | 1383 | MD 94.24 | 45.21, 143.27 | 0.0002 | Fixed effect model |
| hs Troponin I, ng/L | 30 | MD 5.00 | 1.01, 8.99 | 0.01 | Fixed effect model |
| Fibrinogen, mg/dL | 1447 | MD 1.96 | –1.95, 5.87 | 0.33 | Fixed effect model |
| Albumin, g/L | 88 | MD -3.58 | –5.18, –1.98 | <0.0001 | Fixed effect model |
| SOFA score | 135 | MD -1.00 | –4.03, 2.03 | 0.52 | Fixed effect model |
COVID-19 = coronavirus disease 2019, CTPA = computed tomography pulmonary angiography, MD = mean difference, NLR = neutrophil to lymphocyte ratio, PE = pulmonary embolism, SMD = standardized mean difference, SOFA = Sequential Organ Failure Assessment.