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. 2022 Nov 9;42(45):8587–8594. doi: 10.1523/JNEUROSCI.0679-22.2022

Figure 1.

Figure 1.

Mean cross-sectional area per neuron in layer II of the entorhinal cortex. Heights of bars represent the difference in mean cross-sectional area per squared micrometer of layer II neurons in the entorhinal cortex between SuperAgers (N = 6), Younger Controls (N = 6), Normal Elderly (N = 7), and individuals with aMCI (N = 5). An overall average of ∼1044 neurons (SD, 229) were measured per group. SuperAgers showed a significantly larger mean area of layer II ERC neurons compared with Normal Elderly, aMCI individuals, and Younger Controls. There were no significant differences in the mean area of layer II neurons between Normal Elderly, aMCI individuals, and Younger Controls. Statistical significance was assessed using a linear mixed-effect model. Error bars represent the SEM. *p < 0.05; **p < 0.01; *** p < 0.001.