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. 2022 Nov 9;42(45):8587–8594. doi: 10.1523/JNEUROSCI.0679-22.2022

Figure 2.

Figure 2.

Mean cross-sectional area per neuron in layer III/IV of the entorhinal cortex. Heights of bars represent the mean cross-sectional area per square micrometer of layer III/V neurons in the entorhinal cortex among SuperAgers (N = 6), Younger Controls (N = 6), Normal Elderly (N = 7), and individuals with aMCI (N = 5). An overall average of ∼1052 neurons (SD, 53) were measured per group. Mean area of layer III/V ERC neurons was significantly larger in SuperAgers compared with Normal Elderly, aMCI individuals, and Younger Controls. Normal Elderly also showed larger neuronal cross-sectional area in layer III/V of the ERC compared with aMCI individuals and Younger Controls. Statistical significance was assessed using a linear mixed-effect model. Error bars represent the SEM. *p < 0.05; **p < 0.01; ***p < 0.001.