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. 2022 Nov 9;42(45):8587–8594. doi: 10.1523/JNEUROSCI.0679-22.2022

Figure 4.

Figure 4.

Layer II neurons of the entorhinal cortex in SuperAgers, Younger Controls, Normal Elderly, and aMCI individuals. A–D, Layer II neurons in SuperAgers, Younger Controls, Normal Elderly, and individuals with aMCI visualized with cresyl violet staining. A, SA 2, a 90-year-old female SuperAger. B, YC 4, a 57-year-old female young control subject. C, NE 6, an 88-year-old male elderly control subject. D, aMCI 1, an 89-year-old female with aMCI. Scale bar: (in D) A–D, 50 µm. A–D, SuperAger (A) shows a significantly larger mean area of layer II ERC neurons compared with Younger Controls (B), Normal Elderly (C), and individual with aMCI (D).