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. 2020 Sep 1;21(2):286–295. doi: 10.1016/S1473-3099(20)30442-4

Table.

Study characteristics

Total (n=62) Seroconversion studies (n=50) Waning studies (n=12)
Region
Europe 23 (37%) 15 (30%) 8 (67%)
Asia 17 (27%) 17 (34%) 0
North America 13 (21%) 9 (18%) 4 (33%)
Central America 2 (3%) 2 (4%) 0
South America 3 (5%) 3 (6%) 0
>1 region 3 (5%) 3 (6%) 0
Australia 1 (2%) 1 (2%) 0
Study design
Clinical trial 14 (22%) 14 (28%) 0
Follow-up study 13 (21%) 2 (4%) 11 (92%)
Randomised trial 13 (21%) 12 (24%) 1 (8%)
Prospective study 11 (18%) 11 (22%) 0
Randomised controlled trial 11 (18%) 11 (22%) 0
Administration route
Subcutaneous 29 (47%) 28 (56%) 1 (8%)
Intramuscular 1 (2%) 1 (2%) 0
Other* 3 (4%) 3 (6%) 0
Not available 29 (47%) 18 (36%) 11 (92%)
Vaccine (n=87)
MMR-II (Merck) 30 (34%) 20 (28%) 10 (62%)
Priorix 16 (18%) 15 (21%) 1 (6%)
Not available 12 (14%) 11 (16%) 1 (6%)
Triviraten 5 (6%) 5 (7%) 0
Trimovax 5 (6%) 5 (7%) 0
MMR-Vax 3 (4%) 3 (4%) 0
Serum MMR 3 (4%) 3 (4%) 0
Pluserix 2 (2%) 0 2 (13%)
Tresivax 2 (2%) 2 (3%) 0
MMR (Razi Institute) 2 (2%) 2 (3%) 0
Cadila MMR 2 (2%) 2 (3%) 0
Other 5 (6%) 3 (4%) 2 (13%)

87 vaccine combinations were used in the 62 studies identified. MMR=measles-mumps-rubella.

*

Aerosol versus subcutaneous, subcutaneous versus intramuscular, or disposable syringe jet injector versus needle-syringe.

MMR (SPIIPL), Berna MMR, Immravax, JCV-001, or Trivirix.