Table 2.
Analysis of systolic/mean/diastolic arterial pressure, heart rate, glucose and cortisol levels between groups by individual measurements.
| Control group (C) |
M1 group (0.03 mg/kg) |
M2 group (0.06 mg/kg) |
P * | |
|---|---|---|---|---|
| SAP (mm Hg) | ||||
| t0 | 157.0 (18.3) | 155.3 (18.3) | 159.9 (18.2) | .56 |
| t3 | 117.2 (23.7) | 122.6 (21.4) | 138.1 (26.4) †,‡ | .002 |
| t6 | 145.8 (32.7) | 137.0 (28.2) | 147.1 (26.3) | .30 |
| t9 | 131.9 (29.7) | 133.5 (23.7) | 139.9 (24.4) | .41 |
| MAP (mm Hg) | ||||
| t0 | 113.3 (12.9) | 113.2 (14.2) | 115.3 (13.6) | .76 |
| t3 | 85.3 (16.5) | 87.7 (15.5) | 98.5 (18.6)†,‡ | .004 |
| t6 | 105.9 (24.2) | 98.4 (19.7) | 106.7 (18.2) | .20 |
| t9 | 94.6 (20.5) | 95.4 (16.4) | 100.9 (17.5) | .30 |
| DAP (mm Hg) | ||||
| t0 | 91.3 (10.0) | 92.1 (9.0) | 92.9 (7.6) | .75 |
| t3 | 69.4 (13.9) | 70.4 (13.4) | 78.6 (14.0) †,‡ | .01 |
| t6 | 85.9 (20.7) | 79.1 (16.2) | 86.4 (14.4) | .16 |
| t9 | 76.0 (16.5) | 76.4 (13.5) | 81.4 (14.4) | .26 |
| HR (bpm) | ||||
| t0 | 80.2 (10.0) | 76.9 (11.8) | 81.7 (10.9) | .18 |
| t3 | 71.1 (11.9) | 69.6 (11.2) | 71.2 (11.0) | .81 |
| t6 | 80.8 (12.4)‡ | 72.3 (10.2) | 78.6 (13.5) | .01 |
| t9 | 74.3 (12.8) | 69.3 (12.5) | 75.1 (13.9) | .14 |
| GLU (mmol/L) | ||||
| T0 | 5.0 (0.6) | 5.1 (0.6) | 5.1 (0.7) | .68 |
| T1 | 5.7 (0.7) | 5.6 (0.8) | 5.6 (0.9) | .97 |
| T2 | 6.4 (0.7) | 6.1 (0.8) | 6.0 (0.8) | .12 |
| T3 | 4.8 (0.6) | 4.7 (0.5) | 4.8 (0.5) | .81 |
| COR (nmol/L) | ||||
| T0 | 419.5 (134.5) | 397.7 (113.1) | 408.5 (110.3) | .76 |
| T1 | 694.5 (149.9) ‡,§ | 589.6 (122.6) | 545.9 (127.9) | <.001 |
| T2 | 396.4 (128.3) | 371.5 (157.3) | 340.0 (115.2) | .24 |
COR = cortisol, DAP = diastolic arterial pressure, GLU = glucose, HR = heart rate, MAP = mean arterial pressure, SAP = systolic arterial pressure.
*
1-way ANOVA.
†
P < .05 compared to control group.
‡
P < .05 compared to M1 group.
§P < .05 compared to M2 group.