TABLE 2.
Some examples of genetic studies of disease resistance in several major aquaculture fish species.
| Species | Diseases | QTL and candidate genes | References |
|---|---|---|---|
| Atlantic salmon | Infectious pancreatic necrosis (IPN), viral | A single QTL on chromosome 26 explains all the resistance, and NEDD-8 activating enzyme 1 was the candidate causal gene | Moen et al. (2009); Moen et al. (2015); Houston et al. (2010); Pavelin et al. (2021) |
| Pancreas disease (PD), viral | QTL mapped to chromosome 3 and chromosome 7 | Gonen et al. (2015); Hillestad et al. (2020a) | |
| Infectious salmon anemia (ISA), viral | QTL mapped to chromosome 15 | Moen et al. (2007); Li et al. (2011); Gervais et al. (2021) | |
| Cardiomyopathy syndrome, viral | QTL mapped to chromosome 27 | Hillestad and Moghadam, (2019); Hillestad et al. (2020b) | |
| Amoebic gill disease (AGD), parasitic | QTL mapped to various chromosomes 1, 2, 5, 4, 9, 13 | Boison et al. (2019); Aslam et al. (2020) | |
| Sea lice, parasitic | QTL mapped to chromosomes 3, 18, 21 | Robledo et al. (2019) | |
| Rainbow trout | Bacterial coldwater disease | QTL for resistance was mapped to chromosome 19, 8 and 25 | Wiens et al. (2013); Vallejo et al. (2014); Liu et al. (2015); Palti et al. (2015); Fraslin et al. (2019); Liu et al. (2022) |
| Whirling disease | A single QTL was identified on chromosome 9 for resistance | Baerwald et al. (2011) | |
| Columnaris disease (CD), bacterial | Major QTL were mapped to chromosomes 3 and 5 | Calboli et al. (2022); Fraslin et al. (2022) | |
| A major QTL was identified for resistance to rhabdovirus | Verrier et al. (2013) | ||
| White spot disease (WSD), parasitic ciliate Ichthyophthirius multifiliis | Two QTL were identified on chromosome 16 and 17 | Jaafar et al. (2020) | |
| Common carp | RNA-Seq | DEGs related to CyHV-3 disease resistance were identified | Tadmor-Levi et al. (2019a) |
| Common carp | Cyprinid herpes virus disease | QTL mapped to chromosome 14, 30, 43, 44, and 46 | Palaiokostas et al. (2018) |
| Tadmor-Levi et al. (2019b) | |||
| Grass carp | Grass carp reovirus | Resistance against GCRV has high heritability | Huang et al. (2015) |
| Catfish | Enteric septicemia of catfish (ESC) disease, bacterial | QTL were mapped to chromosome 1, 12, and 16 | Zhou et al. (2017); Shi et al. (2018); Tan et al. (2018b) |
| Jin et al. (2022) | |||
| Columnaris disease, bacterial | QTL mapped to linkage group 7, 12, and 14 in genomic hubs | Geng et al. (2015) | |
| Zhang et al. (2020) | |||
| Aeromonas septicemia disease, bacterial | QTL mapped to linkage groups 2, 26, and 29 | Wang et al. (2019) | |
| Asian seabass | Viral nervous necrosis disease (VNN or NNV) | QTL and suggestive QTL were identified | Liu et al. (2016); Yang et al. (2020) |
| Gilthead sea bream | Pasteurellosis disease | Two significant QTL were identified | Massault et al. (2011) |
| Japanese flounder | Lymphocystis disease, viral | Marker-assisted selection | Fuji et al. (2007) |
| Turbot | Aeromonas disease, bacterial | QTLs were identified | Rodríguez-Ramilo et al. (2011) |