TABLE 7.

Patterns of histone modification and regulation of gene expression.

Histone modification	Effect on gene expression	References
H3K4me3	Active promoters	Zhang et al. (2016)
H3K9me3	Gene repression and heterochromatin formation	Bannister et al. (2001)
H3K27me3	Gene repression	Zhang et al. (2015)
H3K36me3	Active genes	Oqani et al. (2019)
H3K79me3	Active transcription	Ooga et al. (2008)
H4K20 me1	Repressive hallmark	Sato et al. (2016)
H3K27ac	Active gene enhancers, often co-exist with H3K4me3	Kang et al. (2021)