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. 2022 Nov 15;12:19577. doi: 10.1038/s41598-022-24011-0

Table 3.

Cellular profiles of BALF and peripheral blood in patients with non-PF-ILDs and PF-ILDs.

Non-PF-ILD
n = 17
PF-ILD
n = 13
P value
BALF cellular profile
Total cell count (/ × 105 ml) 3.02 (1.09) 3.07 (1.45) 0.621
Lymphocytes (%) 23.8 (20.8) 9.8 (5.0) 0.043
Macrophages (%) 73.8 (21.6) 73.6 (31.5) 0.805
Eosinophils (%) 1.3 (2.2) 2.8 (1.7) 0.094
Neutrophils (%) 3.3 (3.2) 7.5 (17.8) 0.072
CD4/CD8 ratio 1.37 (2.04) 1.93 (3.68) 0.408
Th2 cells among conventional CD4+ T cells in BALF (%) 9.0 (7.4) 42.0 (24.2) 0.001
Th2 cells among conventional CD4+ T cells in peripheral blood (%) 35.1 (17.0) 37.9 (25.2) 0.263

BALF bronchoalveolar lavage fluid, PF-ILD progressive fibrosing interstitial lung disease, Th2 T helper type 2.

Data are expressed as medians (interquartile range) unless otherwise stated. Differences between two groups were evaluated by the Mann–Whitney U test.