Supplementary Table 2.
Detailed profile and the ploidy status of the embryos based on PGT-SR and their pregnancy outcome
| Karyotype |
|
PGT-SR embryo status | Number of embryos transferred | Clinical pregnancy/outcome | ||||
|---|---|---|---|---|---|---|---|---|
| Retrieved | MII | Fertilized | Cleaved | Biopsied | ||||
| 46,XX,t(10;14)(p13;q24) | 8 | 8 | 7 | 7 | 3 | 2 x normal Unbalanced (−14, −22) | 1 | Positive/Aborted |
| 46,XX,t(8;12)(p11.2;q24.3) | 13 | 6 | 6 | 6 | 5 | 2 x normal Multiple aneuploidies Unbalanced (−8) Unbalanced (+8, −12) | 2 | Positive/Delivered |
| 46,XX,t(6;7)(q25;q22) | 23 | 12 | 10 | 10 | 5 | 2 x normal Unbalanced (−6, +7, −16) Unbalanced (−6, +7) Unbalanced (−7) | 1 | Negative |
| 46,XY,t(7;17)(p22;p11) | 6 | 6 | 6 | 6 | 4 | Normal 2 X multiple aneuploidies Unbalanced (−17) | 1 | Negative |
| 46,XX, t(1;6)(p36.1;q13) | 15 | 13 | 5 | 5 | 4 | Unbalanced (−6) Mosaic trisomy 6 Multiple aneuploidies Unbalanced (+1, −6) | 0 | NA |
| 46,XY,t(2;17)(q31;p13) | 12 | 11 | 6 | 6 | 3 | Unbalanced (−2) Unbalanced (+2) Normal | 1 | Positive/Delivered |
| 46,XY,t(6;11)(p21;q23) | 7 | 6 | 4 | 4 | 2 | Normal Unbalanced (−6, +11) | 1 | Positive/Delivered |
| 46,XX,t(11;22)(q23;q11.2) | 27 | 22 | 19 | 19 | 6 | Normal Sex chromosome aneuploidy Unbalanced (+11, −22) 2 X unbalanced (−11, +22) Unbalanced (+11) | 1 | Negative |
| 46,XY,t(9;22)(q34;q11) | 21 | 19 | 16 | 15 | 4 | 3 X normal Mosaic partial trisomy 6 (25%) | 2 | Positive/Delivered |
| 46,XX,t(5;9)(q22;p22) | 19 | 10 | 8 | 8 | 7 | 2 X normal 3 X unbalanced (+5, −9) 2 X unbalanced (−5, +9) | 2 | Positive/Delivered |
| 46,XX,t(5;8)(q31;p22) | 16 | 10 | 10 | 10 | 4 | 2 X normal Trisomy 7 Sex chromosome aneuploidy | 2 | Positive/Delivered |
| 46,XX,t(7;13)(p13;q22) | 20 | 19 | 15 | 15 | 6 | Normal 2 X unbalanced (+7, −13) Unbalanced (+7, −13, −11) Unbalanced (−7, +13) Multiple aneuploidies | 1 | Negative |
| 46,XY,t(4;21)(q25;q22) | 6 | 4 | 3 | 3 | 2 | Unbalanced (+4, −21) Unbalanced (−4, +21) | 0 | NA |
| 46,XY,t(4;18)(p12;q11.2) | 11 | 8 | 6 | 6 | 3 | Normal Multiple mosaic aneuploidies Unbalanced (−4, +8) | 1 | Positive/Delivered |
| 46,XY,t(8;15)(q13;q24) | 31 | 20 | 18 | 17 | 4 | Normal Trisomy 6 Trisomy 3 Unbalanced (+8, −15) | 1 | Positive/Delivered |
| 46,XY,t(14;21)(q22;q22.1) | 8 | 4 | 3 | 3 | 3 | Unbalanced (+3; +6) Unbalanced (+14; −21) Unbalanced (−14; +21) | 0 | NA |
| 45,XX,der(13;14)(q10;q10) | 27 | 2 | 1 | 1 | 3 | 2 X normal Multiple aneuploidies | 0 | NA |
| 45,XY,der(13;14)(q10;q10) | 12 | 12 | 9 | 9 | 3 | Normal Multiple aneuploidies Unbalanced (+14) | 1 | Negative |
| 45,XX,der(13;14)(q10;q10) | 16 | 15 | 12 | 12 | 7 | Normal Unbalanced (−16) Unbalanced (+11) Unbalanced (+20) Unbalanced (+13) Unbalanced (−14) Unbalanced (−19) | 1 | Positive/Delivered |
| 46,XY,inv(5)(p15.1q31) | 5 | 4 | 4 | 4 | 3 | Normal Multiple aneuploidies Unbalanced (+5) | 1 | Positive/Delivered |
| 46,XX,inv(10)p11.2q21.2 | 11 | 6 | 5 | 4 | 3 | 2X normal Multiple aneuploidies | 2 | Positive/Delivered |
| 46X,inv(Y)(p11.2;q11.23) | 17 | 16 | 14 | 14 | 3 | 3X normal | 2 | Positive/Delivered |