. 2022 Nov 2;9:992769. doi: 10.3389/fsurg.2022.992769

Table 3.

Predictors of postoperative cognitive dysfunction at 1 week after surgery.

Risk factor	Univariate analyses^a, P	Multivariate logistic regression analysis^b
Risk factor	Univariate analyses^a, P	OR (95% CI)	P
Age	0.017	0.910 (0.021, 0.763)	0.042
Education	0.011	1.198 (0.997, 1.440)	0.054
ACC Time	0.033	0.982 (0.964, 1.001)	0.070
ICU stay	0.030	0.737 (0.47, 1.163)	0.184
Serum NLRP3 level (Immediately after the operation)	0.024	0.128 (0.021 0.763)	0.024
Serum IL-18 level (Immediately after the operation)	0.034	0.042 (0.000, 40.526)	0.533

NLRP3, Nod-like receptor family pyrin domain containing 3; ICU, intensive care unit; CI, confidence interval; OR, odds ratio; ACC, aortic cross-clamping; IL, interleukin.

^{^a,b}

Occurrence of postoperative cognitive dysfunction was modeled as a function of a single predictor and as a function of all significant predictors in the univariate analyses (P ≤ 0.05) respectively.