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Representation of mucosal inflammation in inflammatory bowel disease and inflammatory targets for multiple novel therapies. Therapies are grouped by categories according to their main mechanism of action. Figure created with BioRender.com.
Ig, immunoglobulin; IL, interleukin; JAK, Janus kinase; MAdCAM-1, mucosal vascular addressin cell adhesion molecule 1; S1PR, sphingosine-1-phosphate receptor.
