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. 2022 Nov 2;12:986867. doi: 10.3389/fonc.2022.986867

Table 4.

Predictive power of the ML model and routine clinical models using data of the testing cohort.

Models Specificity Sensitivity Accuracy NPV PPV Recall Youden’s index
Machine learning model 64.4% 87.5% 69.7% 94.6% 42.2% 87.5% 1.519
ALBI 77.8% 55.0% 72.6% 85.4% 42.3% 55.0% 1.328
FIB-4 85.2% 40.0% 74.9% 82.7% 44.4% 40.0% 1.252
APRI 79.3% 45.0% 71.4% 82.9% 39.1% 45.0% 1.243
MELD 90.4% 25.0% 75.4% 80.3% 43.5% 25.0% 1.154
CTP 94.8% 15.0% 76.6% 79.0% 46.2% 15.0% 1.098

ML, machine learning; NPV, negative predictive value; PPV, positive predictive value; ALBI, albumin-bilirubin grade; FIB-4, fibrosis 4 score; APRI, aspartate transaminase to platelet ratio; MELD, model for end-stage liver disease; CTP, Child-Turcotte-Pugh.