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SPTBN1 inhibited PI3K/AKT signaling expression in RA‐FLSs via PIK3R2. The expressions of p‐PI3K, p‐AKT, PI3K, and AKT in RA‐FLSs transfected with Ov‐SPTBN1 and siRNA‐PIK3R2 were detected using western blot. ***p < .001 versus Control group. # p < .05 and ### p < .001 versus Ov‐SPTBN1 group. ∆ p < .05 and ∆∆∆ p < .001 versus Ov‐SPTBN1 + siRNA‐NC group. n = 3. ANOVA followed by Tukey's test. ANOVA, analysis of variance; FLS, fibroblast‐like synoviocyte; RA, rheumatoid arthritis.
