Table 7a. Simplex Model With Contemporaneous B Paths for Activation Level as a Mediator.

Simplex for mediation with contemporaneous b path		SE	p	95% CI
Time-specific outcome / Significant Paths and Effect of treatment	Standardized estimate			LL	UL
Week 2 Depression (Y2)
Total effect	−0.05	0.05	.320	−0.17	0.06
Indirect effect	−0.01	0.01	.379	−0.03	0.01
Week 4 Depression (Y3)
Total effect	−0.08	0.06	.189	−0.20	0.05
Indirect effect	−0.09	0.04	.035	−0.19	−0.001
T→M3→Y3	−0.04	0.02	.006	−0.08	−0.01
Week 6 Depression (Y4)
Total effect	−0.13	0.06	.028	−0.25	−0.004
Indirect effect	−0.12	0.05	.016	−0.22	−0.01
T→M3→Y3→Y4	−0.03	0.01	.005	−0.06	−0.01
T→M3→M4→Y4	−0.04	0.02	.006	−0.08	−0.02
Week 8 Depression (Y5)
Total effect	−0.15	0.06	.012	−0.27	−0.02
Indirect effect	−0.14	0.05	.003	−0.25	−0.04
T→M3→Y3→Y4→Y5	−0.02	0.01	.004	−0.04	−0.01
T→M3→M4→Y4→Y5	−0.03	0.01	.004	−0.05	−0.01
T→M3→M4→M5→Y5	−0.04	0.01	.005	−0.07	−0.01
Week 10 Depression (Endpoint, Y6)
Total effect	−0.22	0.06	< .001	−0.34	−0.09
Indirect effect	−0.16	0.05	.001	−0.26	−0.06
T→M3→Y3→Y4→Y5→Y6	−0.02	0.01	.004	−0.03	−0.01
T→M3→M4→Y4→Y5→Y6	−0.02	0.01	.004	−0.03	−0.01
T→M3→M4→M5→Y5→Y6	−0.03	0.01	.004	−0.05	−0.01
T→M3→M4→M5→M6→Y6	−0.04	0.01	.005	−0.06	−0.01

Note. Only significant paths are shown to save space. Abbreviations: M₃, M₄, M₅ = mediator measurements (taken at Weeks 4, 6, and 8, respectively); SE = standard error; T = Treatment allocation (treatment group = 1, control group = 0); Y₂, Y₃, Y₄, Y₅, Y₆ = outcome measurements (taken at Weeks 2, 4, 6, 8, and 10, respectively).