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. 2021 Sep 30;3(3):e5467. doi: 10.32872/cpe.5467

Table 7b. Simplex Model With Lagged b Paths for Activation Level as a Mediator.

Simplex model for mediation with lagged b path
SE p 95% CI
Time-specific outcome / Significant Paths and Effect of treatment Standardized estimate LL UL
Week 4 Depression (Y3)
Total effect −0.08 0.06 .187 −0.21 0.05
Indirect effect −0.05 0.05 .269 −0.15 0.03
Week 6 Depression (Y4)
Total effect −0.13 0.06 .025 −0.25 −0.01
Indirect effect −0.11 0.05 .033 −0.22 0.001
T→M3→Y4 −0.04 0.02 .01 −0.07 −0.01
Week 8 Depression (Y5)
Total effect −0.16 0.06 .01 −0.28 −0.02
Indirect effect −0.15 0.05 .003 −0.26 −0.04
T→M3→Y4→Y5 −0.03 0.01 .008 −0.05 −0.01
T→M3→M4→Y5 −0.04 0.02 .01 −0.07 −0.01
Week 10 Depression (Endpoint,Y6)
Total effect −0.22 0.06 < .001 −0.35 −0.09
Indirect effect −0.15 0.05 .002 −0.26 −0.04
T→M3→Y4→Y5→Y6 −0.02 0.01 .007 −0.04 −0.01
T→M3→M4→Y5→Y6 −0.03 0.01 .008 −0.05 −0.01
T→M3→M4→M5→Y6 −0.04 0.01 .009 −0.07 −0.01

Note. Only significant paths are shown to save space. Abbreviations: M3, M4, M5 = mediator measurements (taken at Weeks 4, 6, and 8, respectively); SE = standard error; T = Treatment allocation (treatment group = 1, control group = 0); Y2, Y3, Y4, Y5, Y6 = outcome measurements (taken at Weeks 2, 4, 6, 8, and 10, respectively).