Table 1. Demographic and Clinical Characteristics of 1198 Participants Who Survived to Age 24 Months According to Acid Suppressant Use in Early Lifea.
| Characteristic | Participants, No. (%) | |
|---|---|---|
| No acid suppressant use (n = 712) | Acid suppressant ≤24 mo of age (n = 486) | |
| Gestational age at delivery, mean (SD), wk | 26.2 (1.2) | 26.0 (1.3) |
| Sex | ||
| Male | 343 (48.2) | 278 (57.2) |
| Female | 369 (51.8) | 208 (42.8) |
| Weight for gestational age at delivery, z score, mean (SD) | −0.15 (1.0) | −0.19 (1.1) |
| Chronic lung disease | ||
| No oxygen or mechanical ventilation at 36 wk | 383 (53.8) | 207 (42.6) |
| Oxygen at 36 wk | 275 (38.6) | 223 (45.9) |
| Mechanical ventilation at 36 wk | 45 (6.3) | 55 (11.3) |
| White matter damage | 133 (18.7) | 109 (22.4) |
| Maternal race (n = 1179)b | ||
| Black | 220 (30.9) | 102 (21.0) |
| White | 402 (56.5) | 304 (62.6) |
| Otherc | 79 (11.1) | 72 (14.8) |
| Maternal ethnicity (n = 1192)b | ||
| Hispanic | 77 (10.8) | 70 (14.4) |
| Non-Hispanic | 631 (88.6) | 414 (85.2) |
| Maternal education, y (n = 1152)b | ||
| ≤12 | 302 (42.4) | 204 (42.0) |
| >12 to <16 | 168 (23.6) | 102 (21.0) |
| ≥16 | 224 (31.5) | 152 (31.3) |
| Public insurance (n = 1173)b | ||
| No | 421 (59.1) | 288 (59.3) |
| Yes | 282 (39.6) | 182 (37.4) |
| Feeding difficulties at 12 mo (n = 1019)b | ||
| No | 461 (64.8) | 285 (58.6) |
| Yes | 144 (20.2) | 129 (26.5) |
a
Sample that survived to age 24 months and included in inverse probability weighted analyses.
b
Responses did not sum to 1198 because of missing responses.
c
Other included 28 (2.4%) Asian, 12 (1.0%) American Indian, 35 (3.0%) of mixed race, and 76 (6.4%) participants who indicated other on the questionnaire and for whom the racial group could not be determined; these groups were not analyzed individually because data were too sparse for further analysis (data were missing for 19 mothers because no response was given); 147 (12.3%) of 1192 mothers were Hispanic, and 1045 (87.7%) were non-Hispanic (data were missing for 6 mothers because no response was given).