Table 1. No Difference in Body Weight Gain was Observed in TDP-43^A315T Mice and WT Littermate Controls Treated with MSN-LEP-PIO vs PBS^a.

	1 day	2 days	3 days	4 days	5 days	6 days	7 days
WT VH (n = 3)	20.09 ± 0.20	20.63 ± 0.35	21.63 ± 0.32	21.90 ± 0.43	21.87 ± 0.51	22.13 ± 0.47	21.65 ± 0.26
WT L+P (n = 3)	20.10 ± 0.88	19.60 ± 0.70	20.10 ± 0.79	21.13 ± 0.90	20.83 ± 1.30	21.20 ± 0.95	20.42 ± 0.69
TDP-43A315T VH (n = 3)	18.93 ± 0.49	18.80 ± 0.78	18.87 ± 0.83	19.03 ± 0.77	19.40 ± 0.62	19.50 ± 0.69	19.22 ± 0.63
TDP-43A315T L+P (n = 6)	20.17 ± 1.07	19.43 ± 0.97	20.17 ± 0.96	20.63 ± 0.80	20.33 ± 1.12	20.67 ± 0.84	20.46 ± 0.63
WT VH (n = 3)	20.09 ± 0.20	20.63 ± 0.35	21.63 ± 0.32	21.90 ± 0.43	21.87 ± 0.51	22.13 ± 0.47	21.65 ± 0.26

^aBody weight was monitored daily in WT and TDP-43^A315T mice during the 7 day treatment period, and no difference in body weight gain between treatments and groups was observed. Values are expressed as mean ± SEM.