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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: J Bone Miner Res. 2021 Dec 26;37(3):494–504. doi: 10.1002/jbmr.4487

Table 4.

Plasma Analytes in 23-Week-Old Enpp1WT and Dosed and Undosed Enpp1asj/asj Mice

Parameter Unit Enpp1wt + PBS ENPP1asj/asj + PBS Enpp1asj/asj + BL-1118

Calcium mg/dL 6.6 ± 0.5 7.0 ± 0.8 6.9 ± 0.4
Phosphate mg/dL 6.4 ± 0.9 5.7 ± 0.5 5.5 ± 0.8
PTH pg/mL 137 ± 80 229 ± 89 524 ± 248*(↑)
FGF23 pg/mL 172 ± 28 439 ± 215*(↑) 614 ± 167***(↑)
PPi nM 2235 ± 621 51 ± 22**** (↓) 1358 ± 268**(↓)

FGF3 =fibroblastic growth factor 23; PPi = pyrophosphate; PTH = parathyroid hormone.

Text in bold represents abnormal values.

*

p < 0.05,

**

p < 0.01,

***

p < 0.001,

****

p < 0.0001.