Table 3.
Association between type of SARS-CoV-2 variant and total lung lesion burden, as stratified by age
| Outcome: total lung lesion burden (%) | <60 years (n = 423) | 60–75 years (n = 314) | <75 years (n = 263) | ||||
|---|---|---|---|---|---|---|---|
| ß (95% CI) | p | ß (95% CI) | p | ß (95% CI) | p | ||
| Unadjusted | Non-B.1.1.7 lineage | Ref | … | Ref | … | Ref | … |
| B.1.1.7 lineage | 12.6 (8.9–16.3) |
<.001 | 9.5 (5.2–13.8) |
<.001 | 8.1 (3.2–12.9) |
.001 | |
| Adjusted | Non-B.1.1.7 lineage | Ref | … | Ref | … | Ref | … |
| B.1.1.7 lineage | 15.0 (6.7–23.4) |
<.001 | 8.1 (-0.25–16.5) |
.057 | −0.47 (-12.5–11.6) |
.938 | |
BMI, body mass index.
a
Adjusted for sex, BMI, hypertension, diabetes mellitus, hyperlipidemia, smoking status, history of chronic lung disease, heart failure, myocardial infarction, chronic kidney disease, immunodeficiency and serum C-reactive protein level.