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. 2022 Sep 26;19:79.

Table 4.

Pairwise multiple comparisons of Annexin V assay

Reference group Comparison group Statistical significance after(P)

1days 3days 7day
CEM CEM - 0.4a,* <0.0001b,*
SIM 1 <0.0001* <0.0001* <0.0001*
SIM 0.1 0.3 <0.9 0.3
SIM 0.01 <0.0001* <0.0001* <0.0001*
CEM/SIM 1 0.1 0.0003* <0.0001*
CEM/SIM 0.1 <0.0001* <0.0001* <0.0001*
CEM/SIM 0.01 <0.0001* <0.0001* <0.0001*
MTA <0.0001* <0.0001* <0.0001*
Control- <0.0001* <0.0001* <0.0001*
SIM 1 SIM 1 - 0.004a,* <0.0001b,*
SIM 0.1 <0.0001* <0.0001* <0.0001*
SIM 0.01 <0.0001* <0.0001* <0.0001*
CEM/SIM 1 <0.0001* <0.0001* <0.0001*
CEM/SIM 0.1 <0.0001* <0.0001* <0.0001*
CEM/SIM 0.01 <0.0001* <0.0001* <0.0001*
MTA <0.0001* <0.0001* <0.0001*
Control- <0.0001* <0.0001* <0.0001*
SIM 0.1 SIM 0.1 - <0.0001a,* 0.002b
SIM 0.01 0.003* <0.0001* <0.0001*
CEM/SIM 1 <0.9 <0.0001* <0.0001*
CEM/SIM 0.1 0.05 <0.0001* <0.0001*
CEM/SIM 0.01 <0.0001* <0.0001* <0.0001*
MTA <0.0001* <0.0001* <0.0001*
Control- <0.0001* <0.0001* <0.0001*
SIM 0.01 SIM 0.01 - 0.8a 0.07b
CEM/SIM 1 0.01* 0.5 0.2
CEM/SIM 0.1 <0.9 <0.9 <0.9
CEM/SIM 0.01 <0.9 <0.9 0.03
MTA 0.9 0.3 <0.0001*
Control- 0.01* <0.0001* <0.0001*
CEM/SIM 1 CEM/SIM 1 - <0.9a 0.01b
CEM/SIM 0.1 0.1 0.3 0.2
CEM/SIM 0.01 <0.0001* <0.05 <0.0001*
MTA 0.0003* 0.0003* <0.0001*
Control- <0.0001* <0.0001* <0.0001*
CEM/SIM 0.1 CEM/SIM 0.1 - <0.9a 0.1b
CEM/SIM 0.01 0.4 <0.9 0.02*
MTA 0.7 0.1 <0.0001*
Control- 0.001* <0.0001* <0.0001*
CEM/SIM 0.01 CEM/SIM 0.01 - 0.3a <0.9b
MTA <0.9 <0.9 0.7
Control- 0.7 0.002* 0.0006*
MTA MTA - <0.9a <0.9b
Control- 0.3 0.2 0.3

a Comparison between day 3 and 1, b Comparison between day 7 and 3, *Statistically significant, Green: Numerical superiority of the reference group, Red: Numerical superiority of the comparison group, CEM: Bioceramic cement with full concentration, SIM 1: Simvastatin with concentration of 1 μM, SIM 0.1: Simvastatin with concentration of 0.1 μM, SIM 0.01: Simvastatin with concentration of 0.01 μM, CEM/SIM 1: Bioceramic cement containing simvastatin 1 μM, CEM/SIM 0.1: Bioceramic cement containing simvastatin 0.1 μM, CEM/SIM 0.01: Bioceramic cement containing simvastatin 0.01 μM, MTA: Mineral trioxide aggregate