TABLE 5.

Comparison of serum, saliva, and cervical mucus IgA1 and IgG antibody levels to N. gonorrhoeae MS11 and infecting isolates in patients with cervical infections and patients with cervical and rectal infections

Sample	Ig isotype	Visit	Median antibody level (% of total Ig) (range [n])
			Anti-MS11 antibodies		Anti-cervical isolate antibodies
			Cervical infection	Cervical and rectal infection	Cervical infection	Cervical and rectal infection
Cervical mucus	IgA1	1	0.00 (0.00–0.21 [11])	0.16 (0.00–0.45 [6])	0.00 (0.00–0.08 [12])	0.00 (0.00–0.15 [6])
	IgA1	2	0.03 (0.00–1.12 [7])	0.00 (0.00–0.07 [6])	0.07 (0.00–1.97 [7])	0.08 (0.00–0.73 [6])
	IgG	1	0.57 (0.00–12.40 [11])	0.85 (0.41–1.55 [6])	0.09 (0.00–0.94 [11])	0.32a (0.08–2.43 [6])
	IgG	2	0.74 (0.03–2.90 [7])	0.71 (0.00–0.86 [5])	0.00 (0.00–0.07 [7])	0.37b (0.01–1.39 [5])
Saliva	IgA1	1	0.06 (0.00–0.42 [7])	0.04 (0.00–0.09 [5])	0.01 (0.00–0.07 [8])	0.00 (0.00–0.03 [6])
	IgA1	2	0.03 (0.00–0.24 [5])	0.03 (0.01–0.05 [4])	0.01 (0.01–0.20 [5])	0.01 (0.00–0.02 [5])
	IgG	1	0.12 (0.00–1.58 [8])	0.30 (0.00–0.40 [5])	0.26 (0.00–1.91 [8])	0.06 (0.00–0.46 [6])
	IgG	2	0.47 (0.00–1.77 [5])	0.00 (0.00–0.59 [3])	0.15 (0.00–4.30 [5])	0.00 (0.00–0.43 [5])
Serum	IgA1	1	0.01 (0.00–0.02 [12])	0.02 (0.01–0.05 [7])	0.01 (0.00–0.06 [12])	0.01 (0.00–0.09 [7])
	IgA1	2	0.01 (0.00–0.02 [7])	0.02 (0.01–0.05 [6])	0.01 (0.01–0.02 [7])	0.01 (0.00–0.08 [6])
	IgG	1	0.25 (0.14–1.41 [12])	0.28 (0.20–1.13 [7])	0.21 (0.06–3.42 [12])	0.77 (0.00–0.94 [7])
	IgG	2	0.28 (0.13–0.58 [7])	0.33 (0.25–1.29 [6])	0.25 (0.19–0.85 [7])	0.46 (0.08–0.79 [6])

^aP = 0.0782 compared with patients with cervical infection. 

^bP = 0.0303 compared with patients with cervical infection.