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Curcumin and DMC inhibit the activity of HKMTs targeting H3K4. HL60 and U937 leukaemia cells were treated with different concentrations of curcumin (A and B, respectively) or DMC (C and D, respectively). The enzymatic activity of HKMTs targeting H3K4 was calculated as described under methods. Data represent the mean of three replicates ± SD. * and brackets indicate significant difference from the compared concentration at p < .05 using one‐way anova post hoc Bonferroni test
