Table 1. Comparison of the Kinetic Parameters.

compound	KI [nM]	kinact [min–1]	kinact/KI [μM–1 s–1]
JS25	0.77 ± 0.06	0.401 ± 0.064	8.72 ± 1.02
ibrutinib	0.59 ± 0.03	0.041 ± 0.004	1.17 ± 0.13a
acalabrutinib	15.07 ± 0.51	0.038 ± 0.005	0.04 ± 0.01b
BMX-IN-1	1.29 ± 0.50	0.038 ± 0.008	0.49 ± 0.15c

^aValue with a 0.17 deviation from published results (Liclican et al., 2020).⁴⁸

^bValue with a 0.002 deviation from published results (Liclican et al., 2020).⁴⁸

^cValue with a 0.29 deviation from published results (Wang et al. 2017).⁴⁹