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. 2022 Nov 15;21:244. doi: 10.1186/s12933-022-01683-6

Table 5.

Subgroup analysis of TyG index as a continuous variable

Variables N Unadjusted HR(95% CI) Mode 1 HR(95% CI) Mode 2 HR(95% CI) P for interaction
Gender 0.001
 Female 989 1.951 (1.510–2.519) 1.588 (1.202–2.098) 1.544 (1.080–2.208)
 Male 1381 1.117 (0.913–1.366) 1.099 (0.896–1.347) 1.149 (0.893–1.478)
Age (years) 0.545
 < 45 905 1.503 (1.079–2.092) 1.276 (0.882–1.845) 1.247 (0.775–2.005)
 ≥ 45 1465 1.335 (1.121–1.591) 1.229 (1.024–1.475) 1.207 (0.964–1.511)
Disease history 0.034
 No 1619 1.530 (1.225–1.911) 1.368 (1.078–1.735) 1.381 (1.038–1.837)
 Yes 751 1.094 (0.868–1.379) 1.109 (0.872–1.411) 1.229 (0.944–1.599)

Bold P values indicate significance. Mode 1 was adjusted for age and gender. Mode 2 was further adjusted for BMI, SBP, LDL-C, HDL-C, history of hyperlipidemia, hypertension and diabetes based on Model 1

Disease history included hypertension, dyslipidemia and diabetes. The presence of any of such diseases is considered to be having a history

BMI body mass index, SBP systolic blood pressure, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol