Fig. 2.
Overview of the main clinical characteristics, diagnostic results and therapeutic interventions. Legend: White “brains” indicate normal MRI findings and black “brains” indicate pathological MRI findings. White and black “brains” indicate radiological improvement. * indicates the single seizure which occurred in month 1. NMDAR IgG were detected by commercially available CBA (Euroimmun, Lübeck, Germany), titers are provided. Caspr2 IgG were detected by commercially available CBA (Euroimmun; positive at a titer of 1:10). MOG IgG were detected by an in-house CBA [24, 25], titers are provided. Abbreviations: CBA, cell-based assay PLEX = plasma exchange; IVMP = intravenous methylprednisolone; CSF = cerebrospinal fluid; WBC = white blood cells; OCB = oligoclonal bands; MRI = magnetic resonance tomography; FDG = 18F-fluoro-2-deoxy-D-glucose; FET = O-(2[18F]fluoroethyl)-L-tyrosine; PET = positron emission tomography; Caspr2 = contactin-associated protein-like 2; NMDAR = N-methyl-D-aspartate receptors; MOG = Myelin Oligodendrocyte Glycoprotein