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. 2022 Nov 16;22:434. doi: 10.1186/s12883-022-02974-x

Table 1.

Demographic, clinical and serological findings in MOG IgG positive patients with NMDAR encephalitis

Ref Demographics Clinics Serum CSF
Patient Number Age Sex Graus criteria fulfilleda Demyelinating episodes, nb Follow-up, Moc Time E – MOG + , Mo DE symptoms MOG-IgG status NMDAR-IgG status MOG-IgG status NMDAR-IgG status OCB status WBC/µl
[3] 1 48 F Yes 2 60 18 Yes positive positive positive positive positive 150
[3] 2 17 M Yes 2 9 3 Yes n.a Not applicable positive positive negative 3
[3] 3 27 F Yes 5 108 -48 Yes positive negative positive positive positive 66
[3] 4 34 M Yes 2 22 3 Yes positive negative positive positive negative 164
[3] 5 10 M Yes 1 144 -96 Yes positive negative positive positive negative 9
[3] 6 29 M Yes 1 41 36 Yes positive n.a positive positive negative 0
[3] 7 38 M Yes 2 60 -22 Yes positive negative positive positive negative 2
[3] 8 4 F Yes 1 7 0 Yes positive n.a positive positive positive n.a
[3] 9 6 M Yes 1 2,5 0 Yes positive negative positive positive positive 43
[15] 10 9 F Yes 1 18 0.5 Yes positive positive positive positive negative 44
[13] 11 31 M No 2 15 0 Yes positive negative n.a positive negative 8
[12] 12 54 M Yes 0 3 0 Yes positive n.a n.a positive negative 28
[8] 13 3 F Yes 3 252 -240 Yes positive negative positive positive negative 0
[8] 14 23 M Yes 3 44 -44 Yes positive negative negative positive positive 0
[8] 15 6 M Yes 5 54 0 Yes positive positive negative positive positive 8
[8] 16 25 M Yes 1 0 0 Yes positive negative positive positive positive 96
[8] 17 9 M Yes 2 18 18 Yes positive negative negative positive positive 2
[11] 18 47 M n.a 2 60 0 No positive positive positive positive negative 16
[4] 19 36 F Yes 1 44.5 0 No positive n.a n.a positive positive 116
[20] 20 10 F Yes 0 36 12 No positive n.a n.a positive negative 576
[19] 21 6 M Yes 0 3 0 No positive n.a n.a positive positive 0
[18] 22 29 M Yes 1 4 2 Yes positive n.a n.a positive positive 39
[16] 23 12 M Yes 0 1.5 0 No positive positive n.a positive n.a 91
[21] 24 14 F Yes 3 44 -4 No positive positive n.a positive negative 256
[21] 25 10 M Yes 0 6 0 Yes positive positive n.a positive n.a 96
[17] 26 19 M Yes 2 37 18 Yes positive negative negative positive n.a 292
[6] 27 27 M Yes 0 4 0 Yes n.a n.a positive positive n.a 5
[10] 28 38 M Yes 1 6 0 Yes positive positive n.a n.a negative 88
[5] 29 37 M Yes 0 2 0 No positive positive positive positive negative 50
[9] 30 39 M Yes 2 60 0 No positive n.a positive positive n.a 112
[7] 31 30 M Yes 0 12 0 Yes positive positive n.a positive n.a n.a
Total 31 25 (3–54) Female: 8 (25.8%) 29 (94%) 1 (0–5) 18 (0–252) 0 (-240–36) 23 (74%) Positive: 29 Positive: 10 Positive: 16 Positive: 30 Positive: 11 43 (0–576)

Legend: CSF Cerebrospinal fluid, DE Demyelination, E NMDAR-encephalitis, F Female, IgG Immunoglobulin G, MO Months, M Male, MOG Myelin oligodendrocyte glycoprotein, MOG + MOG IgG positivity, N Number, NMDAR N-methyl-D-aspartate receptor, OCB Oligoclonal bands, Ref Reference, WBC White blood cell count

a Diagnostic criteria for definite NMDAR encephalitis according to Graus et al. [26]

b Demyelinating episodes during or after NMDAR-encephalitis were considered

c Follow-Up after NMDAR-encephalitis