Table 2.

Histologic subtyping of available patient samples and PDX models

Patient ID		Histology		Epithelioid subtyping
		(E/B/S)		Predominant architecture		All patterns present		Nuclear grade (Kadota/MSKCC)
		Patient	PDX	Patient	PDX	Patient	PDX	Patient	PDX
Epithelioid	MSK_LX282	E	E	Trabecular	Trabecular	T	T, S	I	I
	MSK_LX627	E	E	Trabecular	Trabecular	T	S	II	II
	MSK_LX703A	E	NA	Tubulopapillary	NA	S, MP, TP	NA	II	NA
	MSK_LX13	E	NA	Solid	NA	S, P*	NA	II	NA
	MSK_LX606	E	E	Solid	Solid	S, TP	S, T	II	II
	MSK_LX333	E	E	Tubulopapillary	Solid	TP, MP, S	S	III	III
	MSK_LX590	E	E	Solid	Solid	S, TP	S, TP	III	III
	MSK_LX678	E	E	Solid	Solid	S	S	III	III
	MSK_LX154	E	E	Solid	Solid	S	S	I	II
	MSK_LX413	E	E	Trabecular	Solid	T, S, TP	S, T	II	III
	MSK_LX570	E	E	Solid	Solid	S, T	S	II	III
	MSK_LX944B	E	E	Tubulopapillary	Solid	TP, T, S	S	II	II
	MSK_LX892	E	NA	Tubulopapillary	NA	TP	NA	I	NA
	MSK_LX19	E	NA	Solid	NA	S	NA	III	NA
	MSK_LX96	E	E	Trabecular	Solid	T, S, TP	S	III	II

Comparative histologic subtyping for the patient (n = 22) and PDX TMA samples (n = 16) with available tissue. For the 15 patient samples with epithelioid histology, the predominant architecture, all architectural patterns/cytologic features present, and nuclear grades were annotated and compared to the 11 available PDX specimens

E epithelioid, B biphasic, S sarcomatoid, PDX patient derived xenograft, MSKCC Memorial Sloan Kettering Cancer Center, Trabecular [T]; Tubulopapillary [TP]; Solid [S]; Micropapillary [MP]; Pleomorphic [P]; not applicable [NA]